For the notorious onychomycosis:
FDA Approves New Treatment for Toenail Fungal Infection
By Kelly Young
Edited by David G. Fairchild, MD, MPH, and Richard Saitz, MD, MPH, FACP, FASAM
The FDA has approved tavaborole topical solution, 5% (Kerydin) to treat onychomycosis of the toenails, the manufacturer announced Tuesday.
The solution is applied with a dropper to the affected toenails once daily for 48 weeks. In two trials of nearly 1200 people with onychomycosis without dermatophytomas or lunula involvement, 7-9% of those treated with tavaborole achieved “complete cure” at 52 weeks, compared with 0.5-1.5% of patients given topical placebo. Side effects included exfoliation, ingrown toenail, erythema, and dermatitis.