Narcolepsy

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Narcolepsy

Narcolepsy: It is a disorder charactorised by excessive day time sleepiness, often disturbed night time sleep and disturbances in the REM sleep. Decrease REM latency is the hallmark; REM sleep occures within 10 mins of onset of sleep. Common age of onset is 15-25 yrs and continues thoughout the life. Tetrad of symptoms: 1) sleep attacks: – Person is unable to resist a sleep (nap) – attack occures during nytime of the day – gap of 2-35hrs betn two naps 2) cataplexy: – char’ by loss of muscle tone in various parts of body. e.g. Drop jaw – may b precipited by sudden emotion 3) hypnagogic hallucinations: – dreal like vivid perceptions which occures at the onset of sleep and associated with fearfullness – these occuring at the time of awakening r called as hypnopompic hallucinations 4) sleep paralysis: – this occures either at awakening or at sleep onset – person is concius bt unable to move his body – episode last for 30 sec to few mins Other associated symptoms are: Fugue states, blackouts, blurring of vision, Narcolepsy Diagnosis: confirmed by polysomnography which shows decreased REM latency Treatment: – forced naps at regular times in the day – stimulant medicatin e.g. Amphetamine or modafinil – anti-depressants
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