TUBERCULIN TEST

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TUBERCULIN TEST *Discovered by Von Pirquet in 1907  Only means of estimating the prevalence of infection in the population *Three main tests in use- Mantoux intradermal test, the Heaf and the Tine multiple puncture test  One TU is equal to 0.00002 mg PPD * WHO advocates a PPD tuberculin known as “PPD-RT-23 with TWEEN 80” * For routine testing the vaccinating teams in India use 1TU of PPD in 0.1 ml on the flex or surface of the forearm, injected intradermally  Result read after 72 hours (3rd day) * Tuberculin reaction consists of erythema and induration (which is measured)  >10 mm Positive  < 6 mm Negative  6-9 Doubtful * If a child below 2 years is found to be positive, it is an indirect evidence of an active tuberculous lesion in the body * Only the elimination of viable TB bacilli result in reversion of tuberculin test to negative
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