Amyloidosis

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Amyloidosis 1. PRIMARY AMYLOIDOSIS  Most common cause of primary amyloidosis – Multiple Myeloma  Most common organ involved in primary amyloidosis – Kidney Most common cause of death in primary amyloidosis – Cardiac  2. SECONDARY AMYLOIDOSIS  Most common cause of secondary amyloidosis – Rheumatoid Arthritis  Most common organ involved in secondary amyloidosis – Kidney Most common cause of death in secondary amyloidosis – Renal 3. FIRST SITE OF AMYLOID DEPOSITS  Kidney – mesangium Liver – space of Disse  Heart – subendocardium
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