Gold Standard

GOLD STANDARD Gold standard method for estimating resting energy expenditure – indirect calorimetry Gold standard investigation for diagnosis of Iron deficiency anemia – Estimation of serum Ferritin Gold standard for proving that the life span of red cell is decreased ( useful in Hemolytic anemia) – Red cell survival study Gold standard for evaluation of stem cell transplantation therapy – Hemopoietic stem cell transplantation Gold standard technique for differentiating allograft rejection and reactivation of disease after heart transplantation – Endo-myocardial Biopsy Gold standard investigation for diagnosis of DVT – Contrast Venography Gold standard investigation for diagnosis of acute pharyngitis – Throat Culture Gold standard investigation for diagnosis of pertussis – Culture of nasopharyngeal secretions Gold standard investigation for diagnosis of Otitis externa caused by P. aeruginosa – Technetium99 bone scan Gold standard investigation for diagnosis of Acoustic Neuroma – Gadolinium MRI Gold standard investigation for diagnosis of Shigella infection – Isolation and identification of pathogen from fecal material Gold standard investigation for diagnosis of Tuberculous meningitis – Culture of CSF Gold standard investigation for diagnosis of HSV Encephalitis – Brain biopsy (CSF PCR largely replaced brain biopsy in recent times) Gold standard investigation for diagnosis of histoplasmosis – Fungal Culture Gold standard investigation for diagnosis of hypertrophic cardiomypathy and atrial myxoma – Echocardiogram Gold standard investigation for imaging heart valves and valve motion abnormalities – 2D echocardiography Gold standard investigation for assessment of Myocardial viability (Identification of ischemic or hibernating myocardium)– PET Gold standard investigation for assessment of LV mass and volume – MRI Gold standard method for evaluation of renal arteries and identification of renal artery lesions – Contrast arteriography Gold standard method for evaluation of respiratory gas exchange – ABG Gold standard investigation for assessment of albuminuria – 24 hr urine collection Gold standard investigation for diagnosis of PNH (Paroxysmal Nocturnal Haemoglobinuria) – Flow cytometry Gold standard investigation for diagnosis of ATTR and other AF mutations – DNA sequencing Gold standard method for identifying and quantifying atherosclerosis in cerebral arteries – X-ray cerebral angiography Gold standard investigation for evaluating anatomy of arterio-venous malformation – X-ray angiography Gold standard for diagnosis and classification of ataxia – genotype Gold standard investigation for diagnosis of of lung infection (Radiotherapy induced) in a cancer patient – open-lung biopsy Gold standard medical treatment for symptomatic progressive pulmonary hypertension – Prostacyclin Gold standard investigation for diagnosis of PIH – Serum Urea Gold standard for assessment of visual impairment – Snellen’s chart Gold standard method of treatment of non-castrate metastatic disease – surgical orchidectomy Gold standard method for bacterial stain analysis – Pulse-field gel electrophoresis Gold standard method of treatment of DCIS – Mastectomy Gold standard approach for resection of anterior and middle mediastinal masses – median or lateral thoracotomy Gold standard method of treatment of Coarctation of aorta – Surgical repair Gold standard method for evaluation of coronary artery disease – Cardiac Catheterization Gold standard method for culture of V. cholerae o139 – Conventional culture method Gold standard to determine cut-off titer of widal test for diagnosis of Typhoid fever – Nested PCR Gold standard treatment of brucellosis in adults – IM Streptomycin + Doxycyclin Gold standard investigation for diagnosis of of chronic arterial mesentric ischemia – Angiography Gold standard method for treatment of chronic ulcerative colitis – Total proctocolostomy with end ileostomy Gold standard method for evaluation of imaging modalities for liver tumors – Intraoperative ultrasonography Gold standard investigation for diagnosis of common bile duct stones – Endoscopic cholangiography Gold standard investigation for measurement of GFR – Inulin clearance Gold standard for treatment of organ confined, muscle invasive, bladder cancer is – Radical cystoprostatectomy in men and anterior pelvic exenteration in woman Gold standard for treatment of femoral shaft fractures – Reamed locked intramedullary nailing Gold standard method in case of difficult intubation – Flexible fibreoptic intubation scope Gold standard method for diagnosis and treatment of Ventilator Associated Pneumonia (VAP) – Broncho alveolar lavage Gold standard treatment of hyperparathyroidism – Surgery Gold standard investigation to differentiate follicular and papillary carcinoma of thyroid gland- Histology Gold standard procedure for thymectomy – Trans cervical mediastinoscopy and surgery Gold standard for treatment of adrenal tumors – Laparoscopic adrenalectomy Gold standard investigation for diagnosis of breast cancer – Mammography Gold standard method for staging of breast cancer – Axillary lymph node dissection Gold standard for evaluation of a stable patient with suspected vascular injury – Angiography Gold standard investigation for diagnosis of GERD – Ambulatory 24 hr PH monitoring Gold standard method for treatment of GERD – Laparoccopic Nissens fundoplication Gold standard for evaluating cure rate in duodenal ulcer patients – Vagotomy Gold standard finding for the diagnosis of GI perforation – Finding pneumoperitoneum Gold standard for diagnosis of Zollinger-Ellison syndrome – Serum gastrin levels( Most patients have serum gastrin levels above 1000pg/mL) Gold standard investigation for diagnosis of colonic mucosal disease – Colonoscopy Gold standard investigation for diagnosis of steatorrhoea – Timed quantitative stool fat determination Gold standard method for treatment of incontinence with an isolated sphincter defect – Overlapping sphincteroplasty Gold standard investigation for diagnosis and method of management of Acute arterial occlusion – Laparotomy Gold standard method for confirmation of mesentric arterial occlusion – Mesentric angiography Gold standard investigation for diagnosis of celiac disease – Small intestine biopsy Gold standard for identifying choledocholithiasis – ERCP Gold standard method of treatment of Symptomatic cholelitiasis – Lap cholecystectomy Gold standard method for diagnosis of Primary sclerosing cholangitis – ERCP Gold standard investigation for diagnosis of Hepatitis C – HCV RNA assay Gold standard test for diagnosis of intraluminal bile duct abnormalities – ERCP Gold standard method for management of hydatid disease – Surgery Gold standard for assessing degree of liver injury and fibrosis – Liver Biopsy Gold standard method for management of blunt hepatic trauma – Non-operative management Gold standard test for assessment of function of sphincter of oddi – Manometry Gold standard investigation of diagnosis of Klatskin tumor – Cholangiography Gold standard investigation for diagnosis of invasive amoebiasis – ELISA